Rose to fame as the lead guitarist of the Los Angeles-based hard rock band Guns N' Roses. His guitar prowess is best exemplified on such tracks as "Sweet Child o' Mine," "Paradise City" and "November Rain."
He was raised by costume designer Ola Hudson and album cover artist Anthony Hudson. His first band was Tidus Sloan, which he joined in 1981.
Apart from Guns N' Roses, he also formed the groups Slash's Snakepit and Velvet Revolver and in 2010, he released his debut, self-titled solo album.
He married actress Renee Suran on October 10, 1992 and later Perla Ferrar on October 15, 2001 until late 2014. He has two sons named London and Cash.
He was asked to join Axl Rose and Izzy Stradlin's new band Guns N' Roses in June 1985, along with Duff McKagan and Steven Adler.