In a memorable moment, he jumped over a KIA and dunked to win the 2011 Slam Dunk Contest.
The son of Tommy and Gail Griffin, he played college basketball with his older brother Taylor at the University of Oklahoma. He has a son named Ford with Brynn Cameron, a former women's NCAA basketball player for USC. In 2017, he began dating Kendall Jenner.
In 2010, he joined center DeAndre Jordan to form a talented front-court for the Clippers.