She dropped out of high school, but continued her education as a home school student.
She appeared on The Celebrity Apprentice in 2009, and worked as a model and a boutique owner. She also starred in the spin-off reality television series Kourtney and Khloé Take Miami and Khloé & Lamar.
She married NBA star Lamar Odom in September 2009 after meeting him at one of Metta World Peace's parties. During a hiatus with Odom, she dated rapper French Montana and NBA star James Harden. In 2016, she began a relationship with Tristan Thompson. She revealed she was expecting her first child in September 2017.